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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Obesity (Silver Spring). 2018 Mar;26(3):485–491. doi: 10.1002/oby.22070

Table 3.

Maternal Cardiometabolic Outcomes in Standard PAT and PAT+ Groups, ITT analysis

Standard PAT (N=134)
median (IQR)
PAT+ (N=133)
Median (IQR)

~15 Weeks ~35 Weeks ~15 Weeks ~35 Weeks
Fasting glucose 80.7 78.1 81.1 77.7
(mg/dL) (76.7, 85.1) (75.4, 83.2) (76.0, 85.3) (73.1, 84.4)
Fasting insulin 9.6 14.2 10.7 15.5
(μU/mL) (6.6, 14.8) (8.8, 19.0) (7.0, 17.0) (9.6, 25.0)
OGIS a 406.5 ± 68.2 388.8 ± 70.4 390.9 ± 73.9 373.2 ± 80.5
Glucose AUC 15047 14488 14946 14604
(mg/dL x 120 min) (13667, 16295) (13524, 16389) (13918, 16269) (13349, 15798)
Insulin AUC 10733 13149 13109 13421*
(μU/mL x 120 min) (8212, 15503) (10625, 17563) (9333, 19339) (8848, 19590)
HOMA-IR 2.0 2.6 2.1 2.9
(1.3, 3.0) (1.6, 3.7) (1.5, 3.4) (1.8, 4.4)
Total cholesterol 158.0 205.0 160.0 198.5
(mg/dL) (142.0, 178.0) (177.0, 225.0) (140.0, 186.0) (179.0, 225.0)
LDL-cholesterol
(mg/dL)a 81.0 ± 23.6 103.4 ± 32.4 83.34 ± 25.63 108.5 ± 36.0
HDL-cholesterol
(mg/dL)a 63.0 ± 13.7 68.0 ± 16.3 63.1 ± 14.0 65.9 ± 15.7
Triglycerides 75.0 145.0 76.0 143.0
(mg/dL) (60.0, 97.0) (125.0, 187.0) (60.0, 98.0) (122.0, 175.0)
SBP (mmHg) 109.0 111.5 112.0 109.7**
(104.0, 119.0) (105.0, 120.0) (105.7, 120.0) (105.0, 117.0)
DBP (mmHg)a 67.0 ± 8.0 69.7 ± 8.9 67.2 ± 8.7 67.5 ± 8.8

OGIS, Oral Glucose Insulin Sensitivity; AUC, area under the curve; HOMA-IR, Homeostasis Model Assessment of Insulin Resistance; LDL, low density lipoprotein; HDL, high density lipoprotein; SBP, systolic blood pressure; DBP, diastolic blood pressure; kg, kilogram SI conversion factors: To convert glucose from mg/dL to mmol/L, multiply by 0.0555; for insulin from μU/mL to pmol/L, multiply by 6.945; for cholesterol from mg/dL to mmol/L, multiply by 0.0259; for triglycerides from mg/dL to mmol/L, multiply value by 0.0113

a

Data are means ± SD

*

Change in value during pregnancy significantly different from Standard PAT group, *P =0.01, **P = 0.02