FIG. 2.

Hematological recovery in RTA 408-treated 7.5 Gy TBI mice. Panel A: Circulating blood cell analysis in RTA 408-treated 7.5 Gy TBI mice 2 and 11 weeks postirradiation. Pooled results from n =7–8 mice are shown. Circulating blood cell analysis in control, non-TBI mice (n =6) is also shown. Although platelets are significantly higher in RTA 408-treated mice, they are still within normal range. Panel B: Nucleated bone marrow cell counts in mice treated with RTA 408 (n =8) 14 weeks post 7.5 Gy TBI and in age-matched, non-TBI controls (n =5). A Student’s t test was used for statistical analysis. *P < 0.05. For all graphs, error bars indicate SEM.