Table 1.
Patient characteristics at baseline
| Characteristics | Study cohorta |
|---|---|
|
| |
| Total patients – no. | 184 |
| Male sex – no. (%) | 76 (41.3) |
| Age – yr | 32.1 (8.9) |
| Race – no. (%) | |
| White | 162 (88.0) |
| African-American | 19 (10.3) |
| Other | 3 (1.7) |
| Hypertension – no. (%) | 75 (41) |
| Height – cm | 172.5 (11.0) |
| BMI – kg/m2 | 25.8 (5.3) |
| Serum creatinine – mg/dL | 0.9 (0.2) |
| Measured GFRb – mL/min/1.73 m2 | 97.6 (23.5) |
| eGFRc – mL/min/1.73 m2 | 93.6 (22.6) |
| htTKV – mL/m | 501.4 (442.9) |
| PKD genotyped – no. (%) | |
| PKD1, truncating (MSG1) and non-truncating MSG2 | 129 (75) |
| PKD1, non-truncating MSG3 | 16 (9.3) |
| PKD2 and NMD | 27(15.7) |
a
Continuous variables are summarized as mean (S.D.) except for htTKV, which is shown as median (interquartile range).
b
Measured by iothalamate clearance and corrected for body surface area
c
Estimated by CKD-EPI formula
d
Total 182 patients (2 missing data). MSG2, mutation strength group 2; MSG3, mutation strength group 3; NMD, no mutation detected