Table 4.
Office BP and ABPM parameters* by BMI category in treated hypertensive subjects
| Normal (BMI<=25) N=123 | Overweight (BMI:25–30) N=249 | Obese (BMI>=30) N=212 | p-value (trend) | p-value (Obese vs Nml) | |
|---|---|---|---|---|---|
| Office SBP | 138.7(135.6,141.7) | 138.3(136.2,140.4) | 140.7(138.4,143.0) | 0.29 | 0.29 |
| Office DBP | 78.6(77.0,80.3) | 79.6(78.4,80.7) | 80.8(79.5,82.0) | 0.12 | <0.05 |
| SBP day | 129.8(127.2,132.4) | 129.7(127.8,131.5) | 130.0(128.0,132.0) | 0.97 | 0.91 |
| SD SBP day† | 13.2(12.6,13.8) | 13.0(12.6,13.4) | 13.1(12.6,13.6) | 0.82 | 0.74 |
| SBP night | 120.5(117.6,123.5) | 120.2(118.2,122.3) | 122.4(120.2,124.7) | 0.35 | 0.32 |
| SD SBP night† | 11.4(10.8,12.0) | 11.0(10.6,11.5) | 11.5(11.0,12.0) | 0.33 | 0.81 |
| SBP 24 hours | 126.6(124.0,129.2) | 126.3(124.5,128.1) | 127.3(125.3,129.3) | 0.78 | 0.70 |
| DBP day | 74.3(72.7,75.9) | 74.6(73.5,75.7) | 73.3(72.1,74.5) | 0.30 | 0.33 |
| SD DBP day† | 8.9(8.5,9.4) | 9.2(8.9,9.5) | 9.3(9.0,9.7) | 0.34 | 0.14 |
| DBP night | 66.5(64.7,68.2) | 66.5(65.3,67.7) | 66.6(65.2,67.9) | 0.10 | 0.94 |
| SD DBP night† | 8.1(7.6,8.5) | 7.9(7.6,8.2) | 8.5(8.2,8.9) | <0.05 | 0.15 |
| DBP 24-hour | 71.6(70.1,73.1) | 71.7(70.6,72.8) | 70.8(69.7,72.0) | 0.56 | 0.45 |
| SBP Non dipping‡ | 1(reference) | 0.731(0.461,1.159) | 0.688(0.424,1.115) | 0.28 | 0.27 |
Statistics reported are reported as mean (95% confidence interval of the mean)
= adjusted for age, gender, smoking, diabetes, high school education and use of anti-hypertensive medications
= also adjusted for daytime/nighttime mean SBP/DBP
= also adjusted for 24-hour mean BP; values shown are odds ratios for being a non-dipper, compared to those with normal BMI.