Table 1.
Images gradinga | Clinical exam positive for RW-ROP | Clinical exam negative for RW-ROP | ||||
---|---|---|---|---|---|---|
| ||||||
No. image sets | Grading positive | Sensitivity (95% CI) | No. image sets | Grading positive | Sensitivity (95% CI) | |
|
||||||
All images graded by reader 1 | ||||||
Reader 1 grading | 582 | 438 | 0.75 (0.70–0.80) | 4583 | 3670 | 0.80 (0.78–0.82) |
Final grading | 582 | 457 | 0.79 (0.73–0.83) | 4583 | 3781 | 0.83 (0.80–0.84) |
P value | 0.03 | <0.001 | ||||
All images graded by reader 2 | ||||||
Reader 2 grading | 434 | 316 | 0.73 (0.6–0.78) | 3353 | 2755 | 0.82 (0.80, 0.84) |
Final grading | 434 | 336 | 0.77 (0.72–0.82) | 3353 | 2792 | 0.83 (0.81–0.85) |
P value | 0.02 | 0.09 | ||||
All images graded by reader 3 | ||||||
Reader 3 grading | 612 | 511 | 0.83 (0.79–0.87) | 6052 | 5005 | 0.83 (0.81–0.84) |
Final grading | 612 | 509 | 0.83 (0.79–0.87) | 6052 | 5059 | 0.84 (0.82–0.85) |
P value | 0.78 | 0.02 |
CI, confidence interval.
Final grading = Trained reader agreed gradings that required no adjudication plus discrepant gradings between readers that required adjudication.