Table 2.
Baseline predictors of all-cause rehospitalization after discharge
| Variable | OR (95% CI)
|
Wald | P-value | ||
|---|---|---|---|---|---|
| Early vs. No readmission | Late vs. No readmission | Early vs. Late readmission | |||
| History of cerebrovascular disease | 1.11 (0.76–1.64) | 1.52 (1.18–1.96) | 0.73 (0.47–1.14) | 10.302 | 0.006 |
| Chronic respiratory disease | 1.51 (1.11–2.07) | 1.25 (0.99–1.58) | 1.21 (0.84–1.76) | 9.254 | 0.010 |
| Prior CRT (with or without ICD) | 1.01 (0.67–1.52) | 1.39 (1.07–1.82) | 0.73 (0.46–1.15) | 5.951 | 0.051 |
| Current smoker vs. never smoked | 0.94 (0.60–1.47) | 1.13 (0.84–1.53) | 0.83 (0.49–1.40) | 0.746 | 0.689 |
| Past smoker vs. never smoked | 1.27 (0.94–1.71) | 1.18 (0.95–1.46) | 1.07 (0.75–1.53) | 4.343 | 0.114 |
| Hospitalization in last year | 1.63 (1.22–2.17) | 1.70 (1.38–2.08) | 0.96 (0.68–1.35) | 34.446 | <0.001 |
| Asia Pacific vs. North America | 0.49 (0.31–0.78) | 0.52 (0.38–0.71) | 0.94 (0.54–1.64) | 23.980 | <0.001 |
| Central Europe vs. North America | 0.11 (0.05–0.28) | 0.19 (0.12–0.30) | 0.60 (0.22–1.70) | 68.157 | <0.001 |
| Latin America vs. North America | 0.47 (0.26–0.85) | 0.60 (0.41–0.87) | 0.78 (0.39–1.56) | 12.625 | 0.002 |
| Western Europe vs. North America | 0.45 (0.24–0.88) | 0.53 (0.34–0.82) | 0.85 (0.40–1.85) | 12.928 | 0.002 |
| Chronic loop diuretic use | 1.46 (1.02–2.09) | 1.94 (1.49–2.52) | 0.76 (0.49–1.17) | 27.453 | <0.001 |
| Hydralazine use | 1.56 (1.03–2.34) | 1.38 (1.01–1.90) | 1.12 (0.69–1.83) | 7.636 | 0.022 |
| Digoxin use | 0.73 (0.52–1.01) | 1.18 (0.96–1.46) | 0.61 (0.42–0.90) | 6.495 | 0.039 |
| Orthopnoea | 1.49 (1.01–2.19) | 0.94 (0.74–1.19) | 1.59 (1.02–2.46) | 4.509 | 0.105 |
| Nitrate use | 1.15 (0.83–1.58) | 0.78 (0.62–1.00) | 1.46 (1.00–2.15) | 4.947 | 0.084 |
| Baseline heart rate, per 5 b.p.m. | 1.00 (0.96–1.05) | 1.03 (1.00–1.06) | 0.98 (0.93–1.03) | 3.497 | 0.174 |
| Baseline weight < 85 kg, per 5 kg | 1.02 (0.95–1.20) | 1.04 (0.99–1.09) | 0.98 (0.90–1.07) | 2.762 | 0.251 |
| Baseline weight ≥85 kg, per 5 kg | 1.01 (0.97–1.04) | 0.97 (0.94–1.00) | 1.04 (0.99–1.09) | 4.368 | 0.113 |
| Baseline sodium, per 5 mmol/L | 0.89 (0.76–1.05) | 0.87 (0.78–0.97) | 1.03 (0.85–1.24) | 7.541 | 0.023 |
CI, confidence interval; CRT, cardiac resynchronization therapy; ICD, implantable cardioverter defibrillator; OR, odds ratio.