Table 4.

All-cause rehospitalization vs. no rehospitalization in relation to 180-day all-cause death

Risk factor	Multivariable
	HR (95% CI)	SE	P-value
Any rehospitalization vs. no rehospitalization	2.38 (1.93–2.94)	0.108	<0.001
History of cerebrovascular disease	1.51 (1.20–1.90)	0.118	0.001
Chronic respiratory disease	1.19 (0.95–1.49)	0.115	0.130
Prior CRT (with or without ICD)	0.83 (0.61–1.12)	0.153	0.212
Baseline heart rate, per 5 b.p.m.	1.00 (0.98–1.03)	0.003	0.861
Current smoker vs. never smoked	0.79 (0.59–1.07)	0.153	0.123
Past smoker vs. never smoked	0.96 (0.80–1.17)	0.098	0.706
Chronic loop diuretic use	1.93 (1.53–2.43)	0.118	<0.001
Hospitalization in last year	1.23 (1.02–1.48)	0.095	0.027
Asia Pacific vs. North America	0.74 (0.57–0.97)	0.138	0.029
Central Europe vs. North America	0.68 (0.48–0.95)	0.173	0.024
Latin America vs. North America	1.22 (0.90–1.65)	0.153	0.198
Western Europe vs. North America	1.18 (0.84–1.66)	0.174	0.337
Hydralazine use	0.89 (0.64–1.25)	0.173	0.504
Baseline sodium, per 5 mmol/L	0.81 (0.73–0.88)	0.010	<0.001
Digoxin use	1.15 (0.95–1.39)	0.097	0.156
Orthopnoea	0.84 (0.69–1.03)	0.104	0.093
Oral/topical nitrate use	1.11 (0.90–1.36)	0.104	0.325
Baseline weight < 85 kg, per 5 kg	0.92 (0.88–0.96)	0.004	<0.001
Baseline weight ≥85 kg, per 5 kg	0.96 (0.92–0.99)	0.004	0.015

CI, confidence interval; CRT, cardiac resynchronization therapy; HR, hazard ratio; ICD, implantable cardioverter defibrillator; SE, standard error.