Figure 1.

Comparison of hemodynamic parameters. IL-11 improved the left ventricular functional recovery of the heart subjected to prolonged cold ischemia during normothermic reperfusion, although no significant difference was observed in any of the values at 30 minutes of reperfusion compared to the control group. (A) LVDP was found to be significantly higher in the IL-11 group at 60, 90 and 120 minutes of reperfusion (P=0.048, 0.03 and 0.03, respectively); (B) +dP/dt was significantly higher in the IL-11 group at 90 and 120 minutes of reperfusion (P=0.046 and 0.02, respectively); (C) −dP/dt was significantly higher in the IL-11 group at 120 minutes of reperfusion (P=0.02). Data are shown as mean ± standard deviation. The comparison between both groups was performed using an unpaired t-test. *, P<0.05 by unpaired t-test. IL-11, interleukin-11; LVDP, left ventricular developed pressure; +dP/dt, peak positive rate of left ventricular pressure rise; −dP/dt, peak negative rate of left ventricular pressure rise.