Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 11;9(1):e3178. doi: 10.1038/cddis.2017.367

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Hypoxia deteriorated G2/M arrest induced by paclitaxel. (a) Cell growth inhibition of paclitaxel treatment under normoxia and hypoxia assessed by MTT assay. Data had been statistically analyzed by Microsoft Excel 2013 and expressed as means±S.D. for three independent experiments. (b) The influence of paclitaxel treatment on cell cycle under normoxia and hypoxia. Summary of the percentage of cells at G0/G1, S and G2/M phase was performed. (c) After 12, 24 and 36 h hypoxic incubation, cyclin A and HIF-1α expression detected by western blottings. Protein expression change was represented by densitometric analysis. The results are representative of three independent experiments and expressed as means±S.D., *P<0.05 and **P<0.01, compared with the control groups