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Cells bearing the tsc2-R1296P mutation are inhibited for growth in fft3 or ypa1 mutant backgrounds. (A) fft3. (B) ypa1. Individual cells of the indicated genotype were seeded (in quadruplicate) onto YES plates. Box and whisker plots describe colony size (arbitrary units) after 3 days' growth on YES medium at 30°C. *P<0.05; **P<0.01; ***P<0.001.
