Table 1.
The antimicrobial prophylaxis regimes used by UK NHS trusts for elective orthopaedic surgery (involving prosthetic joint insertion/insertion of metalwork)
| Antimicrobial regime used | Number of trusts | ||
| 2005 | 2008 | 2011 | |
| Cefuroxime | 121 (79.6%) | 94 (59.9%) | 49 (36.0%) |
| Cefuroxime + gentamicin | 2 (1.3%) | 1 (0.6%) | 1 (0.7%) |
| Cefuroxime + teicoplanin | 1 (0.7%) | 1 (0.6%) | 1 (0.7%) |
| Cefuroxime +/- teicoplanin | – | 1 (0.6%) | 1 (0.7%) |
| Cefuroxime + metronidazole | 2 (1.3%) | 1 (0.6%) | – |
| Other cephalosporins | 8 (5.3%) | 6 (3.8%) | 2 (1.5%) |
| Flucloxacillin | 1 (0.7%) | 2 (1.3%) | 3 (2.2%) |
| Flucloxacillin + gentamicin | 2 (1.3%) | 25 (15.9%) | 44 (32.4%) |
| Flucloxacillin + benzylpenicillin + gentamicin | – | 1 (0.6%) | 1 (0.7%) |
| Teicoplanin | 1 (0.7%) | 1 (0.6%) | 1 (0.7%) |
| Teicoplanin + gentamicin | 2 (1.3%) | 5 (3.2%) | 13 (9.6%) |
| Co-amoxiclav | 4 (2.6%) | 8 (5.1%) | 11 (8.1%) |
| Co-amoxiclav + gentamicin | 1 (0.7%) | 3 (1.9%) | 2 (1.5%) |
| Ertapenem | – | 1 (0.6%) | 1 (0.7%) |
| Vancomycin | – | – | 1 (0.7%) |
| Gentamicin | – | – | 1 (0.7%) |
| Vancomycin + gentamicin | 1 (0.7%) | 1 (0.6%) | – |
| Cefuroxime or vancomycin | 1 (0.7%) | 1 (0.6%) | 1 (0.7%) |
| Cefuroxime or flucloxacillin | 1 (0.7%) | 1 (0.6%) | 1 (0.7%) |
| Cefuroxime or co-amoxiclav | 2 (1.3%) | 2 (1.3%) | 1 (0.7%) |
| Nil formal | 2 (1.3%) | 2 (1.3%) | 1 (0.7%) |
| Total responses | 152 | 157 | 136 |