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. 2018 Feb 26;92(6):e02122-17. doi: 10.1128/JVI.02122-17

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Copyright © 2018 Petrovic et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Genome arrangement of recombinants generated in this study. (A) Prototypic genome arrangement of recombinants. Each recombinant carries the BAC sequence and the α27 promoter-driven EGFP (enhanced green fluorescence protein), bracketed by LoxP sites, cloned in the UL3 and UL4 intergenic region and the scFv to HER2 in appropriate sites of gD as detailed below. The unique long (UL) and unique short (US) portions of the genome, bracketed by terminal (TR) and internal (IR) repeats, along with the location of gB and gH genes, are shown. (B) Specific genotypic modifications of gB and gD genes in each recombinant. (C) Specific genotypic modifications in the gH and gD genes of each recombinant.