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IC50 and bimolecular rate constants of TG2 oxidation by different CXXC proteins
The IC50 value was determined from Fig. 6A, and the bimolecular rate constant was determined from Fig. 6B. ND means not determined.
| Oxidant | IC50 | Bimolecular rate constant |
|---|---|---|
| μm | mm−1 min−1 | |
| PDI | >10 | ND |
| ERp57 | 0.06 ± 0.01 | 162 ± 50 |
| ERp72 | 1.6 ± 0.4 | ND |
| TRX | 5.0 ± 1.9 | ND |
| QSOX1b | >1 | ND |
