Figure 1.

Activation of nuclear factor kappa B and signal transducer and activator of transcription 3 and possible cross talk (indicated by dotted red arrow) in their signaling in periodontal disease. TLR – Toll like receptors, LPS – Lipopolysaccharide, JAK – Janus activated kinase, STAT3 – Signal signal transducer and activator of transcription 3, MYD88 – Myeloid differentiation primary response 88, IXB – its not X but kappa (κ)- the expansion is inhibitor kappa B, P50 – PROTEIN 50, P65 – PROTEIN 65, NFB – nuclear factor-kappa B