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. 2018 Feb 19;9:280. doi: 10.3389/fimmu.2018.00280

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Copyright © 2018 Arrieta-Bolaños, Crivello, Metzing, Meurer, Ahci, Rytlewski, Vignali, Yusko, van Balen, Horn, Falkenburg and Fleischhauer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Complementarity-determining region 3 (CDR3) length analysis of alloresponses against DPB1*02:01 and DPB1*09:01. The length of CDR3 regions (number of amino acids) as determined by immunosequencing for each responder’s (R) samples was quantified. Shown are histograms for the total pre-culture CD4+ cells (left panels) and cultured CD4+CD137+ cells alloreactive against DPB1*02:01 (middle panels) and DPB1*09:01 (right panels).