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. 2017 Dec 27;29(3):1020–1029. doi: 10.1681/ASN.2016090995

Table 3.

Details about aHUS treatment of four women during pregnancies and postpartum period

Patient Preg Year Prospectively Followed Maintenance Plasma Therapy before Pregnancy Plasma Therapy during Pregnancy Start (Gestational Week) Stop (Postpartum Week) TMA Episode
A.1 1 2009 yes none 3 ml/kg twice monthly 15 continued no
2 2012 yes none 3 ml/kg twice monthly 13 continued no
A.2 1 2010 yes none 2.5 ml/kg twice monthly 14 continued no
2 2011 yes none none no
3 2014 yes none none no
C.1 1 2011a no none none yes
2 2014 yes none 10 ml/kg twice monthly 21 14 no
3 2015 yes none 10 ml/kg twice monthly 15 24 no
C.6 1 2002a no none none nob
2 2013 yes 25 ml/kg monthly 25 ml/kg twice monthly 14 19 no
3 2015 yes 25 ml/kg monthly 25 ml/kg monthly 1c yes

Preg, pregnancy.

a

Pregnancy before follow-up at our department.

b

Presented with acute and chronic TMA in renal biopsy 12 mo after delivery.

c

Switch to eculizumab.