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. 2017 Dec 27;29(3):1020–1029. doi: 10.1681/ASN.2016090995

Table 4.

Renal function, BP, and signs of microangiopathic hemolytic anemia during 11 pregnancies

Patient Preg Gestational/pp. weeka Kidney Function Signs of Microangiopathic Hemolytic Anemia Hypertension
A.1 1 13 28 36 3 S-Crea 0.67 0.69 0.69 0.93 Hb 11.1 10.4 10.1 11.7 BP 125/75 120/80 125/80 127/75
UPE 386 320 397 488 PLC 234 182 170 299 Med none
LDH 143 171 165 164
2 14 28 36 3 S-Crea 0.71 0.66 0.71 0.85 Hb 11.8 11.5 10.6 11.8 BP 130/70 130/80 130/80 130/80
UPE 776 727 2208 1178 PLC 237 254 225 317 Med none N N N
LDH 143 202 235 237
A.2 1 13 28 36 5 S-Crea 0.95 0.91 1.06 1.16 Hb 10.1 10.2 10.6 12.1 BP 125/88 125/79 147/105 120/80
UPE 56 112 155 91 PLC 263 172 137 182 Med M M M none
LDH 180 157 207 164
2 14 27 39 2 S-Crea 0.86 0.85 0.85 1.15 Hb 10.5 10.6 11.2 10.9 BP 120/80 120/80 140/90 140/100
UPE 47 164 280 65 PLC 308 254 194 332 Med N N N, M N, M
LDH 169 143 215 215
3 12 28 33 1 S-Crea 0.71 0.8 0.78 0.92 Hb 10.4 10.7 11.9 9.3 BP 125/75 123/84 123/84 130/89
UPE 104 127 145 102 PLC 349 233 258 304 Med N, M N, M N, M N, M
LDH 171 154 191 209
C.1 1 8 25 40 1 S-Crea na 0.5 2.2 Hb 14.1 11.0 9.2 8.0 BP 115/75 110/70 na PRES
UPE neg neg na 362 PLC na na 254 52 Med none na
LDH na 188 1964
2 20 27 37 5 S-Crea 0.76 0.74 0.72 0.9 Hb 12.3 12.1 9.8 11.2 BP 110/90 125/85 125/78 125/78
UPE 110 169 253 390 PLC 235 240 240 368 Med M M M none
LDH 184 164 268 194
3 13 27 37 3 S-Crea 0.74 0.71 0.79 0.89 Hb 11.3 8.9 12.5 11.2 BP 138/102 123/65 126/81 121/71
UPE 373 342 456 290 PLC 333 284 222 335 Med M M M M
LDH 185 205 191 na
C.6 1 8 23 36 na S-Crea na Hb 14.1 12.3 na na BP 110/70 110/70 120/80 na
UPE neg neg neg na PLC 272 243 na na Med none
LDH na
2 14 28 38 3 S-Crea 1.46 1.71 2.01 1.96 Hb 10.0 8.4 8.9 9.3 BP 130/85 130/88 132/83 140/93
UPE 101 85 202 366 PLC 279 236 191 398 Med U, H, N U, L, N U, L, N U, Ca, A
LDH 154 na 184 215
3 13 29 37 1 S-Crea 1.66 2.06 2.42 7.53 Hb 9.9 8.5 9.6 6.8 BP 155/95 133/71 135/90 158/82
UPE 212 244 2848 7653 PLC 263 177 178 108 Med U, L, N U, L, N U, L, N U, Ca, A
LDH 146 182 246 592

Preg, pregnancy; pp., postpartum; S-Crea, serum creatinine (mg/dl); Hb, hemoglobin (mg/dl); BP, BP (mmHg); UPE, urinary protein excretion (mg/g creatinine); PLC, platelet count (G/L); Med, medication; LDH, lactate dehydrogenase (U/L); N, Nifedipin; M, Methyldopa; na, not available; PRES, posterior reversible encephalopathy syndrome; neg, urine dipstick negative; U, urapidil; H, hydrochlorothiazide; L, labetolol; Ca, carvedilol; A, amlodipine;

a

Columns 1–3 refer to gestational week; column 4 refers to postpartum week.