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Human albumin did not modify the effects of IS during short or long incubations. Analysis of ABCB1 mRNA and P-gp activity in HepG2 cells incubated with IS or KCl (A and B) during 16 hours in the presence of human albumin or (C–F) for 96 hours with or without albumin. Results represent the mean±SEM of five independent experiments. *P<0.05; **P<0.01; ***P<0.001.
