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Inhibition of Hsp90 in control and delCHIP mpkCCD cells support a role of CHIP in AQP2 degradation. (A) Representative immunoblots from mpkCCD cells treated with the Hsp90 inhibitor 17-AAG. (B) Summary of 17-AAG data from three independent experiments. Asterisks indicate significance relative to control conditions within an individual cell line. ***P<0.001; ****P<0.001; ####P<0.001 (significance between cell lines).
