Table 1.
Outcomes of patients by treatment group
| Outcome Parameter | Early, n=112 | Delayed, n=119 | P Value | Absolute Difference Early − Delayed [95% CI], % | OR, Early Versus Delayed [95% CI] |
|---|---|---|---|---|---|
| Primary outcome | |||||
| MAKE 1 yr,a no./no. total (%) | 72/111 (64.9) | 106/119 (89.1) | <0.001 | −24.2 [−34.7 to −13.7] | 0.23 [0.11 to 0.45] |
| Secondary outcomes | |||||
| 1-yr all-cause mortality, no. (%) | 56/111 (50.2) | 83/119 (69.8) | <0.01 | −19.6 [−32.0 to −7.2] | 0.62 [0.44 to 0.87] |
| Requirement of RRT 1 yr, no./no. total (%) | 4/55 (7.3) | 4/36 (11.1) | 0.71 | −3.8 [−16.2 to 8.5] | 0.62 [0.15 to 2.69] |
| PRD 1 yr,b no./no. total (%) | 16/55 (29.1) | 23/36 (63.9) | 0.001 | −34.8 [−54.6 to −15.0] | 0.23 [0.09 to 0.57] |
a
MAKE is defined as mortality at 1 yr, RRT at 1 yr, and PRD defined as 25% decline in eGFR.
b
PRD defined as 25% decline in eGFR.