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. 2018 Feb 15;29(3):806–824. doi: 10.1681/ASN.2017080890

Figure 2.

Figure 2.

Nephron and interstitial progenitor markers mix and persist into epithelializing nephrons. (A and D) Immunofluorescent stains for CITED1 and SIX2 in mouse and human kidneys. Insert in (D) shows CITED1 protein in the human RV (scale bar, 10 µm). (B, C, E, and F) Quantitative analyses of signal intensity distribution for CITED1 and SIX2. (G–L) Immunofluorescent analysis for FOXD1 and SIX2 and intensity correlation plots for these. White, blue, and red dashed lines indicate ureteric bud epithelium, cap mesenchyme, and nascent nephrons, respectively. Scale as indicated on fields. CM, cap mesenchyme; IM, interstitial mesenchyme; N, nephron; PTA, pretubular aggregate; RV, renal vesicle; UB, ureteric bud.