Skip to main content
. 2018 Feb 15;29(3):806–824. doi: 10.1681/ASN.2017080890

Figure 7.

Figure 7.

Single-cell transcriptional profiling of human nephrogenic niche cells. (A) tSNE plot displaying principal component analysis of approximately 2800 human kidney cortex cells from week 16 kidney. Cell identities as indicated on figure by gene expression. Dashed line demarks the nephron progenitors. (B) Cluster hierarchies inferred from differential gene expression and GO-term analyses of top 50 differentially expressed genes per cluster. (C) tSNE plot displaying principal component analysis of cells from cluster 4 in (A). (D) Cluster hierarchies inferred from differential gene expression and GO-term analysis of top 50 differentially expressed genes per cluster as seen in (C). (E) tSNE plots displaying gene expression levels in cells. (F–J) Gene expression plots for novel and established NPC markers. Genes as indicated on plots. tSNE, t-Distributed Stochastic Neighbor Embedding.