Table 2.
First point of detection for commonly used protein markers of mature tubule segments in the human kidney
| Gene Symbol | Gene Name | Stage First Observed | Gudmap Ontology Number |
|---|---|---|---|
| LRP2 | LDL Receptor Related Protein 2 | Proximal segment of SSB | 27764 |
| SLC3A1 | Solute Carrier Family 3 Member 1 | Proximal segment of SSB; early proximal tubule | 27764; 27784 |
| SLC12A1 | Solute Carrier Family 12 Member 1 | Immature loop of Henle ascending limb | 35426 |
| SLC12A3 | Solute Carrier Family 12 Member 3 | Early distal tubule (after capillary loop stage) | 28390 |
| CUBN | Cubilin | Early proximal tubule | 27784 |
| PODXL | Podocalyxin Like | Proximal renal vesicle; visceral epithelium of SSB | 31549; 27766 |
| WT1 | Proximal renal vesicle; visceral epithelium of SSB; proximal segment of SSB | 31549; 27766; 27764 | |
| NPHS2 | Podocin | Visceral epithelium of SSB | 27766 |
| MAFB | Proximal renal vesicle; visceral epithelium of SSB | 31549; 27766 | |
| UMOD | Uromodulin | Early distal tubule (after capillary loop stage) | 28390 |
| AQP1 | Aquaporin 1 | Early proximal tubule (after capillary loop stage) | 27784 |
Proteins detected in figures are summarized and related to data on whether proteins are causative of human or mouse kidney disease/phenotype.