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. 2018 Feb 26;8:3635. doi: 10.1038/s41598-018-21650-0

Table 6.

Linear regression analysis between gene expression levels and body parameters.

Multivariant analysis Body Parameter r r2 F p
% Bone 0.86 0.75 23.6 <0.001
% Fat 0.59 0.34 4.2 0.004
Femoral VKDP Genes: % Soft tissue 0.48 0.23 2.5 0.05
Gas6 % Brown Adipose Tissue 0.64 0.41 5.2 0.001
Periostin % Calcified soft tissue 0.89 0.79 29.2 <0.001
Mgp % Lung Tissue 0.40 0.16 1.5 NS
Ggcx % Lung airways 0.63 0.40 3.6 0.02
Vkor Length 0.67 0.45 6.6 <0.001
Mass 0.68 0.46 6.7 <0.001
% Bone 0.61 0.37 10.5 <0.001
Aortic VKDP Genes: % Fat 0.44 0.19 4.3 0.009
Mgp % Soft tissue 0.36 0.13 2.7 0.05
Ggcx % Brown Adipose Tissue 0.53 0.28 6.7 0.001
Vkor % Calcified soft tissue 0.78 0.60 27.1 <0.001
% Lung Tissue 0.26 0.07 1.3 NS
% Lung airways 0.20 0.04 0.5 NS
Length 0.62 0.38 11.0 <0.001
Mass 0.62 0.39 11.3 <0.001
% Bone 0.76 0.57 16.7 <0.001
Aortic Non-VKDP Genes: % Fat 0.73 0.53 14.3 <0.001
Sclerostin % Soft tissue 0.65 0.43 9.4 <0.001
Bmp-1 % Brown Adipose Tissue 0.61 0.37 6.8 <0.001
ER alpha % Calcified soft tissue 0.85 0.72 32.1 <0.001
Angiotensinogen % Lung Tissue 0.27 0.07 0.9 NS
% Lung airways 0.33 0.11 1.1 NS
Length 0.71 0.51 13.0 <0.001
Mass 0.69 0.47 11.1 <0.001
Femoral VKDP and Aortic VKDP Genes % Bone 0.88 0.78 15.5 <0.001
combined % Fat 0.67 0.45 3.5 0.004
% Soft tissue 0.58 0.34 2.3 0.05
% Brown Adipose Tissue 0.72 0.52 4.5 0.001
% Calcified soft tissue 0.92 0.85 25.0 <0.001
% Lung Tissue 0.50 0.25 1.4 NS
% Lung airways 0.64 0.41 2.0 0.09
Length 0.78 0.60 6.6 <0.001
Mass 0.77 0.59 6.3 <0.001
Femoral and all Aortic Genes % Bone 0.93 0.87 15.9 <0.001
combined % Fat 0.82 0.67 4.8 <0.001
% Soft tissue 0.77 0.59 3.4 0.004
% Brown Adipose Tissue 0.82 0.67 4.4 0.001
% Calcified soft tissue 0.95 0.90 21.1 <0.001
% Lung Tissue 0.66 0.43 1.8 NS
% Lung airways 0.84 0.70 3.1 0.02
Length 0.82 0.68 4.9 <0.001
Mass 0.83 0.68 5.0 <0.001

% values are as percentage of total body volume. NS: Not statistically significant.