Table 2.
Diagnostic categories and disease course of patients with multiple sclerosis
| RRMS (n=176, 94.62%)
|
|||||
|---|---|---|---|---|---|
| More than one NEE | One NEE with one MRI (DIS) and other MRI (DIT) | One encephalopathic and one NEE | A single NEE with one MRI (DIS and DIT) (≥12 years) | SPMS (n=10; 5.38%) | |
| Total, n (%) | 103/176 (58.52%) | 24/176 (13.64%) | 17/176 (9.66%) | 32 (18.18%) | 10 (5.38%) |
| Sex (F) | 67 | 16 | 9 | 19 | 4 |
| Age at onset (years), median (mean ± SD) | 13 (14.01±2.02) | 12 (12.93±3.67) | 11 (11.14±1.46) | 13 (14.96±1.28) | 12 (12.62±3.07) |
| Initial EDSS, median (IQR) | 3 (2.5–4) | 3 (2–3.5) | 3 (2–4) | 2 (1.5–3) | 3 (2–3.5) |
| Last observed EDSS, median (IQR) | 3.5 (3–4) | 3.5 (2.5–4) | 3 (2.5–4) | 3 (2–4) | 6 (5.75–6.5) |
Abbreviations: DIS, Dissemination in space; DIT, Dissemination in time; EDSS, expanded disability status scale; F, females; IQR, interquartile range; MRI, magnetic resonance imaging; MS, relapsing remitting multiple sclerosis; NEE, Non-encephalopathic event; SPMS, secondary progressive multiple sclerosis.