Table 2.
Effect of PSDE and PSNH in acetic acid induced writhing test.
| Group | Dose | Writhing number | Inhibition (%) |
|---|---|---|---|
| Control | 10 mL/kg | 22.00 ± 2.62 | 0.00 ± 0.00 |
| DS | 100 mg/kg | 2.60 ± 0.74∗$ | 88.68 ± 3.61∗$ |
| PSDE | 200 mg/kg | 12.80 ± 3.30∗ | 44.08 ± 15.78∗ |
| PSDE | 400 mg/kg | 10.20 ± 3.29∗ | 57.86 ± 12.37∗ |
| PSNH | 200 mg/kg | 9.20 ± 1.01∗ | 59.86 ± 6.23∗ |
| PSNH | 400 mg/kg | 5.80 ± 2.03∗ | 75.53 ± 8.36∗ |
All of the experimental values are denoted as mean ± SEM. ∗P < 0.05 versus control (Dunnett's t-test). $P < 0.05 versus PSDE 200 mg/kg (pairwise comparison by post hoc Tukey's HSD test).