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. Author manuscript; available in PMC: 2018 Nov 13.
Published in final edited form as: Cancer Cell. 2017 Nov 13;32(5):654–668.e5. doi: 10.1016/j.ccell.2017.10.005

Figure 8. Therapeutic targeting of granulocytes and macrophages.

Figure 8

A. Tumor growth in mice treated with JNJ-40346527 (CSF1R inhibitor), SB225002 (CXCR2 inhibitor), or their combination. Mean and SD are shown. Each group included 5 mice. Significance was calculated using two-way ANOVA test. B. The presence of TAM and PMN-MDSC in B16F10 tumors. **-p<0.01 from control (n=4). C. LLC TB mice were treated with inhibitors and PD-1 antibody (100 μg twice a week). Mean and SD are shown. Each group included 4–5 mice. Significance was calculated using a linear mixed-effect model with the random effect at individual animal level.