Fig. 6.
Activation of YPMS@PpIX@FA after UV365nm-exposure induces release of ROS and death of cancer cells. a For cytotoxicity analysis cells were grown, treated with varying concentration of nanoparticles for 24 h and irradiated with different dose of UV. Toxicity was analyzed by MTT assay 24 h after UV exposure. Generation of cellular ROS on YPMS@PpIX@FA treated TRAMP-C1 cells upon UV irradiation: (b) fluorescent microscopy image, (c) flow cytometry analysis. Results are expressed as the mean ± SEM of three independent experiments. ns not significant, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 using a 2-way ANOVA with a Tukey posttest