. Author manuscript; available in PMC: 2018 Feb 27.

Published in final edited form as: Clin Rev Allergy Immunol. 2017 Feb;52(1):1–19. doi: 10.1007/s12016-015-8510-y

Table 4.

Prevalence of necrotizing myopathy in anti-SRP-positive PM/DM

Author	Country	Year	Anti-SRP test method	N=(anti-SRP+)	Necrotizing myopathy (%)
Miller [52]	UK	2002	IP	7	100
Hengstman [51]	European countries	2006	IP/dot blot for 7SL RNA	15	(73?)
Takada [53]	Japan	2009	IP	11	(82?)
Aggarwal [55]	USA	2015	IP anti-SRP54 ELISA (12 % were negative)	26	92
Suzuki [56]	Japan	2015	IP anti-SRP54 ELISA (18 % were negative)	100	84

SRP signal recognition particle, IP immunoprecipitation, ELISA enzyme-linked immunosorbent assay