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. Author manuscript; available in PMC: 2018 Feb 27.
Published in final edited form as: Annu Rev Pharmacol Toxicol. 2012 Sep 28;53:127–146. doi: 10.1146/annurev-pharmtox-010611-134548

Figure 1.

Figure 1

Evolution of the pharmacological specificity concept. Abbreviations: GHS, growth hormone secretagogue; GPCR, G protein–coupled receptor; OFQ/N, orphanin FQ or nociceptin; NOP, OFQ/N receptor; NPS, neuropeptide S.