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. 2018 Feb 26;15:12. doi: 10.1186/s12989-018-0248-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Hydrodynamic particle size distribution. The hydrodynamic size of the particles was determined with NanoSight LM20 and the Nanoparticle Tracking Analysis software 3.0. Particles used in the ex vivo study was dispersed in DMEM (a). Particles used in the in vivo study was dispersed in 0.45 μm filtered sterile water added 2% FBS (b). The data are presented as the mean particle size (nm) from three independent experiments. On each experimental day the mean of five following measurements were used