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. 2018 Feb 26;15:12. doi: 10.1186/s12989-018-0248-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — 5-hydroxytryptamine(5-HT)-induced receptor-dependent vasocontraction of rat aorta segments exposed ex vivo to particles. The 5-HT response is expressed as the % maximal contraction induced by stimulation with K⁺ before the dose-response measurements. Each point on the curve represents the cumulative response at each concentration of 5-HT. The data are presented as the mean ± SEM, n indicates the number of animals. An asterisk (*) denote a statistically significant effect on E_max compared to the control group (P < 0.05)