Fig. 7.

LPS induced A549 cell apoptosis by regulating CASC2/miR-144-3p/AQP1 axis. The A549 cell was transfected or co-transfected of pcDNA-CASC2, miR-144-3p mimic and pcDNA-AQP1 and induced by LPS. And then the cell apoptosis was detected by MTT, and demonstrated by caspase-3 expression. a The inhibited cell apoptosis by pcDNA-CASC2 was reversed by miR-144-3p mimic, while which was reversed again by pcDNA-AQP1. b The caspase-3 expression by western blot. c A549 cell apoptosis in different groups using flow cytometry assay. *P < 0.05 vs pcDNA, ^#P < 0.05 vs pre-NC, ^&P < 0.05 vs miR-144-3p mimic