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. Author manuscript; available in PMC: 2018 Feb 27.
Published in final edited form as: Brain Res. 2014 Aug 28;1585:51–62. doi: 10.1016/j.brainres.2014.06.021

Figure 5. Gene expression and correlation of NMDA receptor subunits in the RVLM.

Figure 5

Bar graphs compare the gene expression of NMDA receptor subunits NR1 (A), NR2A (C), NR2B (E), NR2C (G) and NR2D (I) in spinally-projecting RVLM neurons between sedentary and active rats measured by real-time qRT-PCR. Data presented as fold change ± S.D. Correlation was determined between the total running distance in active animals and fold change of NMDA receptor subunits NR1 (B), NR2A (D), NR2B (F), NR2C (H), and NR2D (J) in spinally-projecting RVLM neurons. Gene expression of NR2C showed a positive correlation trend towards the total running distance (p = 0.06) suggesting that physical activity could contribute to NR2C neuroplasticity in the RVLM.