Table 5. Univariate and multivariate analysis of prognostic factors for esophageal NEC.

	Univariate		Multivariate
	HR (95%CI)	P-value	HR (95%CI)	P-value
Age, years (< 58 vs. ≥ 58)	1.3 (0.1–15.2)	0.79
Gender (male vs. female)	0.75 (0.39–1.44)	0.74
Tumor site (middle vs. others)	1.34 (0.25–7.89)	0.62
Tumor size (> 5cm vs.< 5cm)	1.05 (0.05–23.2)	0.98
Gross type (variable)	0.33 (0.75–2.66)	0.44
Depth of invasion (continuous variable)	0.51 (0.05–5.17)	0.26
Lymph node metastasis (yes vs. no)	14.74 (1.26–172.4)	0.02	6.86 (2.22–21.21)	0.01
Differentiation (continuous variable)	0.11 (0.01–3.32)	0.21
Treatment (CT vs. no CT)	0.37 (2.96–6.75)	0.48
Distant Metastasis (yes vs. no)	33.1 (2.02–543.5)	0.01	15.6 (3.14–77.62)	0.01