Fig. 2.

Landscape of PBMC circRNA expression. (a) A Venn diagram of the parental genes with circRNA transcripts among PBMCs, platelets, RBCs, and whole blood. (b) Distribution of log₂-transformed TPM values of circular transcripts in PBMCs, platelets, RBCs, and whole blood. (c) The fraction of RNA-seq reads from coding linear, non-coding linear, and circular transcripts. (d) The cumulative distribution of TPM values of circular transcripts. A significantly increased circRNA TPM was observed in the TB patients compared with the healthy controls. The P-values were computed by the Kolmogorov-Smirnov test.