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. 2018 Feb 26;18:16. doi: 10.1186/s12866-018-1156-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Porphyromonas gingivalis (P. gingivalis) ATCC 33277 infection enhances MIF secretion in EA.hy926 cells. EA.hy926 were challenged with Escherichia coli (E. coli) lipopolysaccharide (LPS, 1 μg/mL) or P. gingivalis (MOI = 100) for 4, 10 or 24 h. MIF levels was analyzed using ELISA. Infection of P. gingivalis significantly increased MIF secretion in EA.hy926 cells. EA.hy926 were incubated with medium only as a control. E.coli LPS was used as a positive control. The I bar shows the standard deviation. *P < 0.01