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. 2018 Feb 27;18:17. doi: 10.1186/s12866-018-1160-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Characterization of the fibronectin and collagen binding T-antigen (FCT) regions. The vast majority of the SDSE-isolates harboured two FCT-regions, denoted FCT₁ and FCT₂, respectively. Three structurally different variants of the FCT₁-region were detected, designated A, B and C. Of these, variant A was identified in 51 out of 53 isolates, although some variations were observed; the fibronectin binding protein Gfba was absent in 24 isolates, whereas Ancillary protein 1 along with the two downstream Sortase enzymes were absent in 11 isolates. The FCT₁ variants A, B and C detected in our SDSE isolates resembled the S. pyogenes variants FCT-6, FCT-5 and FCT-1, respectively.¹⁵ The FCT₂ region had a conserved genetic composition, but was absent in five isolates. The figure is drawn to scale