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. 2018 Jan 1;32(1):20–25. doi: 10.1101/gad.307736.117

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© 2018 Thakur and Henikoff; Published by Cold Spring Harbor Laboratory Press

This article, published in Genes & Development, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

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Figure 2. — Heterogeneous protection of centromeric α satellites in N-ChIP. (A) Fragment length analysis of 250-bp × 250-bp merged pairs obtained from native salt fractionation ChIP-seq data sets on D7Z1 (top) and DXZ1 (bottom) in various fractions. (B, top panel) An example of a contig containing dimeric α-satellite units arranged in tandem. CENP-A profiles were generated by mapping merge pairs to D7Z1 and DXZ1 arrays. (Bottom three panels) A region spanning two tandem 340-bp dimers from the contigs is presented. Magenta boxes represent CENP-B boxes.