Table 4.
The bivariable and multivariable Cox regression analysis of predictors of mortality among HIV positive children on ART in Amhara Regional State referral hospitals, Ethiopia from January 1st, 2012 - February 28th, 2017
| Variables | Survival status Dead Censored |
CHR (95%CI) | AHR (95%CI) | |
|---|---|---|---|---|
| Sex | ||||
| Male | 23 | 154 | 2.5 (1.3, 5.0) | 1.3 (0.6, 3.0) |
| Female | 15 | 198 | 1 | 1 |
| Age | ||||
| < 1yer | 3 | 8 | 4.9 (1.4, 17.0) | 2.5 (0.6, 9.9) |
| 1-5 years | 17 | 99 | 2.2(1.1, 4.3) | 1.7(0.7, 3.7) |
| 5-15 years | 18 | 245 | 1 | 1 |
| Residence | ||||
| Urban | 35 | 298 | 1 | 1 |
| Rural | 3 | 54 | 0.6(0.2, 2.0) | 0.5(0.1, 1.7) |
| OI at baseline | ||||
| Yes | 30 | 152 | 4.3 (2.0,9.0) | 1.9 (0.8, 4.5) |
| No | 8 | 200 | 1 | 1 |
| WHO clinical staging | ||||
| Stage I and II | 8 | 221 | 1 | 1 |
| Stage III and IV | 30 | 131 | 5.6 (2.6, 12.3) | 2.6 (1.1, 6.6)** |
| CD4 count or percent | ||||
| Below the threshold | 33 | 2410 | 3.2 (1.2, 8.2) | 5.2 (1.9, 14.1)** |
| Above the threshold | 5 | 112 | 1 | 1 |
| Hemoglobin level | ||||
| < 10 g/dl | 15 | 32 | 6.2 (3.2, 11.9) | 3.2 (1.4, 7.4)** |
| ≥ 10 g/dl | 23 | 320 | 1 | 1 |
| Underweight | ||||
| Normal | 10 | 242 | 1 | |
| Moderate (WAZ < − 2 | 13 | 66 | 4.2 (1.8, 9.6) | 2.4 (0.9,6.4) |
| Severely (WAZ < −3) | 15 | 44 | 6.8 (3.01, 15.2) | 1.3 (0.5, 3.6) |
| Stunting | ||||
| Normal | 12 | 254 | 1 | 1 |
| Moderate (HAZ < −2) | 8 | 39 | 3.9 (1.6, 9.7) | 2.3 (0.9, 6.29) |
| Severe (HAZ < −3) | 18 | 59 | 6.1 (2.9, 12.9) | 3.9 (1.7, 9.4)** |
| Wasting | ||||
| Normal | 18 | 269 | 1 | 1 |
| Moderate (WHZ or BAZ < −2) | 5 | 44 | 1.5 (0.5, 4.0) | 1.2 (0.4, 3.6) |
| Severe (WHZ or BAZ < −3) | 15 | 39 | 4.5 (2.2,9.0) | 3.0 (1.3, 6.9)** |
**Significant predictors in the multivariable analysis