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. Author manuscript; available in PMC: 2018 Oct 24.
Published in final edited form as: Cell Rep. 2017 Oct 24;21(4):1077–1088. doi: 10.1016/j.celrep.2017.10.001

Figure 5. Tissue-Specific Targeting across All Tissues.

Figure 5

(A) Heatmap depicting the results from gene set enrichment analyses on targeting profiles for all possible transcription factor (TF)-tissue pairs, grouped by the community assignment of the GO terms and TF-tissue pairs.

(B) Word clouds summarizing the processes contained in each community.

(C) An illustration of the tissues associated with each community. Edge width indicates the number of transcription factors identified as differentially targeting at least one GO term in the community in a particular tissue. For simplicity, we only illustrate connections to tissues that include five or more transcription factors.

(D) Heatmap of transcription factors significantly associated with one of the nine largest communities; the grayscale gradient represents the probability that a transcription factor would be associated with a community by chance given a random shuffling of community assignments.

See also Table S6 and Figures S5 and S6.