Table 5.
Methylation/transcription correlations of CpG sites differentially methylated by suicide attempt severity.
| FTO-cohort (n = 11) |
||||
|---|---|---|---|---|
| Robust linear regression | ||||
| Gene | Transcript | Illumina ID | Coef. | p |
| CRH | NM_000756 | cg19035496 | – | ns |
| CRH | NM_000756 | cg23409074 | 3.70 | 2.69E − 02 |
The table lists CpG-sites located within the TSS2000 of HPA-axis genes with significant Suicidality-dependent methylation changes. These methylation probes are investigated for a correlation with transcription in a separate cohort of 11 healthy non-fasting controls. Methylation M-values were correlated with expression values inter-individually, by robust linear regression models. Abbreviations: Coef., regression coefficient; ns, not significant; p, p-value.