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. 2018 Feb 6;115(8):E1809–E1818. doi: 10.1073/pnas.1716582115

Table 1.

TAC proteins and reagents

Name Gene ID Source Information
BBA4 (34) - Decorates a structure of the basal- and probasal body
- Stably associates with isolated flagella
This study - Loss of BBA4 after p197 RNAi
p166 Tb927.11.3290 (21) - First discovered TAC component
- Transmembrane domain (residue 1,440–1,462)
- Localizes between kDNA and basal body (PCF)
- kDNA missegregation/growth retardation after RNAi (PCF)
- Stably associates with isolated flagella
This study - Phenotype in BSF and not essential in BSF γL262P cells
Mab22 (28) - Decorates a protein in the EZFs and mature/probasal body
p197 Tb927.10.15750 (27) - Localizes between kDNA and basal body (PCF)
- kDNA missegregation/growth arrest after RNAi (PCF)
This study - Localizes to the EZFs
- Phenotype in BSF and not essential in BSF γL262P cells
TAC40 Tb927.4.1610 (22) - Beta-barrel OM protein
- kDNA missegregation/growth arrest after RNAi (BSF, PCF)
- kDNA missegregation (BSF γL262P)
- Localizes between kDNA and basal body
- Stably associates with isolated flagella
TAC102 Tb927.7.2390 (20) - Localizes to the ULFs
- kDNA missegregation/growth arrest after RNAi (BSF, PCF)
- kDNA missegregation (BSF γL262P)
- Stably associates with isolated flagella
TAC65 Tb927.5.830 (26) - Localizes to the EZFs
- kDNA missegregation/growth arrest after RNAi (PCF, BSF)
- kDNA missegregation (BSF γL262P)
- Stably associates with isolated flagella
This study - Localizes to the EZFs
TAC60 Tb927.7.1400 (38) - OM protein with two transmembrane domains
- kDNA missegregation/growth arrest after RNAi (BSF, PCF)
- kDNA missegregation (BSF γL262P)
- Localizes between kDNA and basal body
- In complex with TAC40
- Stably associates with isolated flagella