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. Author manuscript; available in PMC: 2018 Feb 27.
Published in final edited form as: Cytometry B Clin Cytom. 2015 May 23;88(4):214–226. doi: 10.1002/cyto.b.21243

Table 3.

Progenitor Stage Results. Files that had enough events to analyze were modeled to obtain critical stage locations for markers CD38, CD19, and CD10 with units of cumulative percent. The recorded results for ten study files are shown above. Markers were deemed to be on the same stage boundary if their correlation coefficients, r, were significant and their standardized differences, t, were not (see bottom of table).

P1 P2 and P3
Files graphic file with name nihms943244t7.jpg graphic file with name nihms943244t8.jpg graphic file with name nihms943244t9.jpg
B_BM1.fcs 67.4 68.0 69.3
B_BM7.fcs 3.9 10.0 11.5
B_BM8.fcs 7.7 37.8 36.0
B_BM9.fcs 2.5 33.5 27.2
B_BM10.fcs 43.0 85.8 86.0
B_BM11.fcs 33.5 72.0 71.4
B_BM12.fcs 48.5 86.1 83.1
B_BM14.fcs 46.0 47.5 46.8
B_BM15.fcs 46.9 100.0 99.9
B_BM16.fcs 2.3 18.3 22.3
  μ 30.2 55.9 55.4
  σ 24.0 30.9 30.6
  r 0.99
 H0: r=0 <0.00001
  t 0.62
 H0: t=0 N.S.

The up-regulation of CD38 (see a) was found to represent the end of the first stage boundary, P1 (red). The up-regulation of CD19 (see b) and CD10 (see c) were found to occur together forming the end of stage P2 and beginning of stage P3.