Table III. PWHO Neuropsychiatric Outcomes by PWS Genetic Subtype.

Primary Psychiatric Diagnoses	UPD15 (N=29)	Deletion (N=36)	Odds# UPD15	95% CI	p-value*
Any Psychotic Features	9(31%)	7(19%)	1.9	0.60,5.8	0.28
Bipolar Disorder (Nonpsychotic)	8(28%)	5(14%)	2.4	0.68,8.2	0.17
Anxiety Disorder	12(41%)	13(36%)	1.2	0.46,3.4	0.66
Major Depressive Disorder	5(17%)	10(28%)	0.5	0.16,1.8	0.32
Intermittent Explosive Disorder	8(27%)	12(33%)	0.8	0.26,2.2	0.62
Excoriation (skin picking) Disorder	10(34%)	11(30%)	1.2	0.42,3.4	0.74

^#Odds ratio for UPD15 relative to deletion subtype using Logit.

^*p<0.05 considered significant

Additional diagnoses included: attention deficit hyperactivity disorder, conduct disorder and tic disorders.