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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Mol Cell Neurosci. 2017 Nov 28;87:46–54. doi: 10.1016/j.mcn.2017.11.016

Figure 1. Schematic of Polycomb and Trithorax Related Proteins at Promoters of Repressed and Active Genes.

Figure 1

Repressed genes are bound by Polycomb group proteins (PcG) whereas Trithorax-related proteins (TrxG) localize to actively transcribed genes. COMPASS (complex of proteins associated with Set1) opposes PcG activity to activate transcription. ATP-dependent chromatin remodelers (CHD, ISWI, INO80, and SWI/SNF) regulate DNA accessibility, which influences gene repression and activation during embryonic development.