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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Curr Opin Chem Biol. 2017 Dec 21;42:138–146. doi: 10.1016/j.cbpa.2017.12.005

Figure 1.

Figure 1

Schematic representation of the MS imaging and IMS techniques that have been integrated for enhanced imaging of metabolites, lipids and proteins from biological tissues. MS imaging techniques highlighted include MALDI, DESI, LMJ-SSP, LESA and LAESI. IMS techniques include DTIMS, TWIMS and FAIMS. 2D ion images of metabolites (adenosine diphosphate and adenosine monophosphate), lipids (Gangliosides GD1 (d18:1/18:0) and GT1 (d18:1/18:0)), and proteins (ubiquitin and hemoglobin α) obtained using MS imaging and IMS are shown [26,28,56].