Figure 2.
Progression of motor alterations in 13a2-aSyn female and male mice. On the challenging beam (A), errors per step increased with age in female 13a2-aSyn mice. For spontaneous activity (B) rears decreased with age in male 13a2-aSyn mice. *, ** represents p<0.05, 0.01, respectively, compared to WT at same age. Δ, ΔΔ represents p< 0.05, 0.01 compared to 2m within the same genotype. 4×3 Mixed design ANOVA, Tukey’s HSD post hoc. N-sizes= 14–15 per genotype.