Table 4.
Association between TLR10 tagSNPs and risk of TB in ATAPC.
SNP | Additive model |
Dominant model |
Recessive model |
|||
---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
rs10004195 | 0.870 (0.742–1.020) | 0.086 | 0.772 (0.602–0.991) | 0.042 | 0.905 (0.689–1.187) | 0.470 |
rs11096956 | 0.836 (0.711–0.985) | 0.032 | 0.825 (0.653–1.042) | 0.106 | 0.732 (0.536–1.001) | 0.051 |
rs11466617 | 0.691 (0.578–0.826) | 4.86 × 10−5 | 0.696 (0.555–0.873) | 0.002 | 0.434 (0.280–0.671) | 1.77 × 10−4 |
rs11466655 | 0.956 (0.767–1.191) | 0.686 | 0.920 (0.722–1.173) | 0.501 | 1.372 (0.604–3.116) | 0.449 |
rs4129009 | 0.748 (0.622–0.903) | 0.002 | 0.735 (0.619–0.902) | 0.008 | 0.565 (0.343–0.931) | 0.025 |
rs11096957 | 1.100 (0.930–1.302) | 0.267 | 1.123 (0.886–1.424) | 0.337 | 1.144 (0.829–1.578) | 0.414 |
rs11466653 | 1.287 (1.008–1.643) | 0.043 | 1.285 (0.983–1.678) | 0.066 | 1.977 (0.737–5.306) | 0.176 |
P-values significant after Bonferroni correction (P < 0.0071) are shown in bold.
SNP, single-nucleotide polymorphism; OR, odds ratio; CI, confidence interval.
P-values were calculated using multivariate logistic regression with age and gender set as covariates.