Table 1.
Clinical and demographic characteristics of patients who developed colorectal cancer at the index AA/TSA/ASSA resection site n (%)
| Characteristics | Developed CRC (n = 84) | No CRC (n = 252) | P value1 |
| Demographics | |||
| Male sex | 56 (66.7) | 138 (54.8) | 0.06 |
| Age, yr (≥ 70) | 40 (47.6) | 85 (33.7) | 0.02 |
| Time interval from first treatment for advanced adenoma till cancer or last surveillance colonoscopy in years (median, IQR) | 4.24 (1.51-7.23) | 6.0 (4.05-9.35) | < 0.01 |
| Number of colonoscopies between first polypectomy and cancer (mean ± SD) | 1.65 ± 2.30 | 1.47 ± 1.6 | 0.83 |
| Adenoma size (1-2 cm) | 31 (42.5) | 146 (58.2) | 0.03 |
| Adenoma size (> 2 cm) | 20 (27.4) | 27 (10.8) | 0.0007 |
| Flat/sessile | 76 (91.6) | 161 (66.8) | < 0.01 |
| Degree of dysplasia | |||
| High grade | 28 (33.3) | 66 (26.2) | 0.18 |
| Low grade/no dysplasia | 56 (66.7) | 186 (73.8) | 0.18 |
| Number of attempts to remove the polyp (mean ± SD) | 2.05 ± 1.62 | 1.26 ± 0.60 | < 0.01 |
| Number of polyps resected (> 3 polyps) | 14 (16.7) | 21 (8.3) | 0.03 |
| Polypectomy device used | |||
| Hot snare | 19 (24.1) | 41 (16.3) | 0.11 |
| Cold snare | 5 (6.3) | 26 (10.3) | 0.11 |
| Snare NOS | 60 (75.9) | 185 (73.4) | 0.11 |
| Additional treatments | |||
| Piecemeal removal | 21 (27.6) | 30 (13.1) | < 0.01 |
| Mucosal lift | 13 (17.1) | 23 (10.0) | 0.10 |
| Polyp location | |||
| Right colon | 63 (75.0) | 110 (43.7) | < 0.01 |
| Left colon | 8 (9.52) | 106 (42.1) | < 0.01 |
| Rectum | 13 (15.5) | 36 (14.3) | < 0.01 |
1
P-values for continuous variables were obtained using the Kruskal-Wallis Test; Pearson’s χ2 test was used for discrete variables. CRC: Colorectal cancer.